a Record control number WOS:000329569100002

a ISSN 0165-8107

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number WL140

b Item number .S37 2013

a Personal name Aykan, Umit.

h Medium Electronic Document

a Title Screening for Patients with Mild Alzheimer Disease Using Frequency Doubling Technology Perimetry

c Statement of responsibility, etc Ümit Aykan, M.Orçun Akdemir, Özlem Yıldırım, Figen Varlıbaş

b Name of publisher, distributor, etc Informa Healthcare,

c Date of publication, distribution, etc 2013.

a Summary, etc We compared the visual field performances of patients with mild Alzheimer disease (AD) with normal subjects and detected visual field impairment attributable to the magnocellular pathway using frequency doubling technology-Matrix (FDT-Matrix). We recruited 43 patients with mild AD (mean age: 68.0 +/- 7.2 years) and 33 controls who are visually and cognitively normal (mean age: 64.1 +/- 6.4 years). All participants had at least two reliable FDT-Matrix 30-2 tests. Reliability indices, global indices (mean deviation and pattern standard deviation), and glaucoma hemifield test results were measured with FDT-Matrix. The mean test duration was significantly longer in patient group compared with controls (p = 0.002). Among the reliability indices, false negatives were higher in patient group than controls (p = 0.003). There were statistically significant differences in mean deviation and pattern standard deviation values (p<0.0001 and p<0.0001, respectively) and glaucoma hemifield test results (p<0.001) between the patient and the control group. Our results imply that the pathogenesis of cognitive deterioration may not only be confined to the cortical area but also to the magnocellular pathway. We underline that FDT testing can be useful for the identification of early impairment and the follow-up of patients with AD.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Clinical Neurology

a Topical term or geographic name as entry element Alzheimer Disease.

a Topical term or geographic name as entry element frequency doubling technology;

a Topical term or geographic name as entry element magnocellular pathway;

a Topical term or geographic name as entry element visual field tests

a Topical term or geographic name as entry element Optıc-Nerve

a Topical term or geographic name as entry element Contrast Sensıtıvıty;

a Topical term or geographic name as entry element Retınal Pathology

g Relationship information Dec 2013, Vol.37, Issue:6, p.239-246

t Title Neuro-Ophthalmology

x International Standard Serial Number 01658107

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.3109/01658107.2013.830627